I don't have a big history of dealing with same-sex attracted people. I can only think of two cases where I interacted with someone that I knew was gay.
One was back when I briefly lived in San Antonio, sharing an apartment with a (heterosexual) high school friend of mine. Dave had a friend who was (1) gay and (2) needed a ride. I was fine with giving a ride for a friend of a friend, saying something like "as long as you don't make a pass at me, we're just fine." to the guy's face. No problem, I wasn't his type anyway.
That was before becoming "born-again" but I'd have the same approach today.
The other one was at the flower shop my mom worked at. One of her co-workers was gay, but he was also arguably the best floral designer in town. It was a non-issue at work, even with the boss being an old-school Nazarene lady; it was a "poorly kept secret" that wasn't discussed. Had their been same-sex weddings when he was on board (he's retired now), he'd have been just the person to finesse the issue with, letting the old-school folks pass on servicing it.
He was a nice guy who got along well with my Vineyard pastor when the pastor would up rooming with him in the hospital after Pastor Milton had a heart attack. Had the issue not been discussed at the dinner table over the years, he would have been just another middle-aged guy on the occasions I saw him while visiting the shop.
Other than that, I can't recall dealing with any gays. I surely have dealt with some others, but they don't come with ID badges; the guys who are so "flaming" that they'd set off the smoke detector are largely things of fiction, at least in small towns. Had I spent more time in bigger cities, I might have run into more situations. Given the number of students I've taught, I undoubtedly have taught a few, and have probably worked with a few as well, but it has yet to be a work issue, since is isn't an issue in processing health insurance paperwork or learning about business principles.
Had it become an issue, they'd still be children of God, worthy of respect. Not necessarily approval for their sex lives, but respect. They'll have things to answer for with God, but we all will, which would be the subject of a non-workplace related conversation if the conversation happened at all.
Since I'm unlikely to work as a baker, a florist or a photographer, I don't see myself being ask to service a same-sex wedding. Other commercial transactions don't generally have sexual overtones; the preferences of a customer at McDonalds that matter are whether they prefer to supersize it or not.